- vs Aston Villa
Sun Nov 8, 4:30 PM UTC · Premier League · England · Old Trafford, Manchester
- at Liverpool
Sun Nov 22, 4:30 PM UTC · Premier League · England · Anfield, Liverpool
- at Sporting CP
Wed Nov 25, 8:00 PM UTC · UEFA Champions League · World · Lisbon
- vs Brentford
Sat Nov 28, 3:00 PM UTC · Premier League · England · Old Trafford, Manchester
- at Newcastle
Wed Dec 2, 8:15 PM UTC · Premier League · England · St. James' Park, Newcastle
- vs Coventry
Sat Dec 5, 3:00 PM UTC · Premier League · England · Old Trafford, Manchester
- vs RB Leipzig
Tue Dec 8, 8:00 PM UTC · UEFA Champions League · World · Old Trafford, Manchester
- at Crystal Palace
Sun Dec 13, 7:00 PM UTC · Premier League · England · Selhurst Park, London
- at Arsenal
Sun Dec 20, 4:30 PM UTC · Premier League · England · Emirates Stadium, London
- vs Nottingham Forest
Sun Dec 27, 4:30 PM UTC · Premier League · England · Old Trafford, Manchester
- vs Sunderland
Wed Dec 30, 7:30 PM UTC · Premier League · England · Old Trafford, Manchester
- at Brighton
Sat Jan 2, 12:30 PM UTC · Premier League · England · Amex Stadium, Brighton
- vs Newcastle
Thu Jan 7, 8:00 PM UTC · Premier League · England · Old Trafford, Manchester
- at Aston Villa
Sat Jan 16, 3:00 PM UTC · Premier League · England · Villa Park, Birmingham
- vs Bayern München
Wed Jan 20, 8:00 PM UTC · UEFA Champions League · World · Old Trafford, Manchester
- vs Liverpool
Sat Jan 23, 3:00 PM UTC · Premier League · England · Old Trafford, Manchester
- at Villarreal
Wed Jan 27, 8:00 PM UTC · UEFA Champions League · World · Estadio de la Ceramica, Villarreal
- at Brentford
Sat Jan 30, 3:00 PM UTC · Premier League · England · Brentford Community Stadium, London
- vs Chelsea
Sat Feb 6, 3:00 PM UTC · Premier League · England · Old Trafford, Manchester
- vs Brighton
Wed Feb 10, 8:00 PM UTC · Premier League · England · Old Trafford, Manchester
- at Nottingham Forest
Sat Feb 20, 3:00 PM UTC · Premier League · England · City Ground, Nottingham
- vs Arsenal
Sat Feb 27, 3:00 PM UTC · Premier League · England · Old Trafford, Manchester
- at Sunderland
Wed Mar 3, 8:00 PM UTC · Premier League · England · Stadium of Light, Sunderland
- vs Everton
Sat Mar 13, 3:00 PM UTC · Premier League · England · Old Trafford, Manchester
- at Manchester City
Sat Mar 20, 3:00 PM UTC · Premier League · England · Etihad Stadium, Manchester
- vs Hull City
Sat Apr 10, 2:00 PM UTC · Premier League · England · Old Trafford, Manchester
- at Ipswich
Sat Apr 17, 2:00 PM UTC · Premier League · England · Portman Road, Ipswich
- vs Crystal Palace
Sat Apr 24, 2:00 PM UTC · Premier League · England · Old Trafford, Manchester
- at Coventry
Sat May 1, 2:00 PM UTC · Premier League · England · Coventry Building Society Arena, Coventry
- at Bournemouth
Sat May 8, 2:00 PM UTC · Premier League · England · Vitality Stadium, Bournemouth
- vs Leeds
Sat May 15, 2:00 PM UTC · Premier League · England · Old Trafford, Manchester
- at Tottenham
Sun May 23, 2:00 PM UTC · Premier League · England · Tottenham Hotspur Stadium, London
- vs Fulham
Sun May 30, 3:00 PM UTC · Premier League · England · Old Trafford, Manchester
